手性THz超表面传感器对乳酸对映体的灵敏检测

Sensitive determination of lactic acid enantiomers by a chiral terahertz metasurface sensor

摘要:

基于柔性扭曲双层手性超表面传感器，采用太赫兹时域光谱技术，以手性乳酸(LA)对映体为研究对象，提出一种在太赫兹波段实现手性物质浓度传感和对映体识别的方法。结果表明，手性超表面传感器的圆二色谱(TCD)会随着浓度的增加而发生偏移，且不同的手性对映体偏移量不同，左旋性LA(L-LA)和右旋性LA(D-LA)的最高检测灵敏度分别为2.6 GHz/(mg/mL)和1.9 GHz/(mg/mL)，检测限低至0.01 mg/mL。手性超表面传感器在LA传感和手性识别方面的巨大潜力，为手性对映体的灵敏检测提供了一种高效、低成本的技术方法。

Abstract:

Based on a flexible twisted bilayer chiral metasurface sensor, utilizing terahertz time-domain spectroscopy technology, with chiral Lactic Acid(LA) enantiomers as the research subjects, a method for sensing the concentration of chiral substances and enantiomer recognition in the terahertz band is proposed. The results show that the Transmission Circular Dichroism(TCD) of the chiral metasurface sensor shifts with the increase of concentration, and the shift amounts are different for different chiral enantiomers. The highest detection sensitivity for Levorotatory Lactic Acid(L-LA) and Dextrorotatory Lactic Acid(D-LA) are 2.6 GHz/(mg/mL) and 1.9 GHz/(mg/mL), respectively, with a detection limit as low as 0.01 mg/mL. The great potential of the chiral metasurface sensor in LA sensing and chiral recognition provides an efficient, low-cost technical method for the sensitive detection of chiral enantiomers.