Abstract:Orthogonal Frequency Division Multiplexing(OFDM), Single Carrier with Frequency Domain Equalization(SC/FDE) and Multiple-Input Multiple-Output(MIMO) are the key techniques of next generation wireless communication. In this paper, the principles, research history and key issues of the above techniques are summarized, and OFDM research hotspots are analyzed in detail. Their applications in telemetry are discussed. Finally, it is concluded that OFDM should be widely used for aeronautical telemetry, and MIMO shows an enormous application potential for many telemetry systems, and Single Carrier Frequency Domain Equalization(SC-FDE) will be a new robust scheme for aeronautical and missile telemetry because it is very suitable to the environments of power-limited and severe multipath interference.