Terahertz metamaterials with high sensitivity for biological tissue slices study

Abstract:

Terahertz(THz) wave has great development potential in biomedical science due to its nonionizing, labelless and real-time characteristics. To distinguish biological tissues with similar permittivity, a metamaterial with Fano resonance is designed and fabricated for THz reflection imaging. The simulation and experimental results show that the reflection sensitivity of the metamaterial is 132 GHz/RIU at 0.82 THz. The metamaterial not only enhances the contrast of imaging resolution plate, but also improves the contrast between the muscle and the fat tissues by approximately 7.5%, therefore, it can improve the contrast of biological tissue slice images. This work has established an experimental and theoretical foundation for future terahertz applications in clinical tissue samples.